HSC 70 Polyclonal Antibody, 20ul[BT-AP10168] ROS/Nitric Oxide Detection Several alternatively spliced transcript variants

Several alternatively spliced transcript variants of ACAD10 have been described

Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner

The encoded protein contains a homeobox DNA-binding domain

Mutations in this gene are implicated in Bardet-Biedl syndrome

and is involved in calcium transport and calcium signaling in renal epithelial cells

HSC 70 Polyclonal Antibody, 20ul[BT-AP10168] ROS/Nitric Oxide Detection Several alternatively spliced transcript variantsThis gene encodes a member of the heat shock protein 70 family, which contains both heat inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin coated vesicles during transport of membrane components