SSH3 Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification This gene contains at least

This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons

Interacts with NCDN

Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF)

CDK11B encodes a member of the serine/threonine protein kinase family

Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression

SSH3 Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification This gene contains at leastThe ADF (actin depolymerizing factor) cofilin family (see MIM 601442) is composed of stimulus responsive mediators of actin dynamics. ADF cofilin proteins are inactivated by kinases such as LIM domain kinase 1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF cofilin proteins in vivo.