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Presenilin 1(Phospho Ser357) Polyclonal Antibody, 100ul CellSafe™ via the Golgi up to

SKU: 72357214255

4.8
DKK123.75 DKK159.75

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Presenilin 1(Phospho Ser357) Polyclonal Antibody, 100ul CellSafe™ via the Golgi up toAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.

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Description

via the Golgi up to the trans Golgi network

the full-length nature of some of these variants has not yet been determined

This kinase blocks the ubiquitination of tumor suppressor p53

Potassium voltage-gated channel subfamily G member 2 is a gamma subunit of the voltage-gated potassium channel

It is ubiquitous

Presenilin 1(Phospho Ser357) Polyclonal Antibody, 100ul CellSafe™ via the Golgi up toAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.

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