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NAGS Rabbit Polyclonal Antibody, 20ul sgRNA customized design Activated by phosphorylation on Thr-211

SKU: 72479841365

4.5
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NAGS Rabbit Polyclonal Antibody, 20ul sgRNA customized design Activated by phosphorylation on Thr-211The N acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N acetylglutamate (NAG) from glutamate and acetyl coenzyme A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI) the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and thereby CPSI activity. Deficiencies in N acetylglutamate synthase have been associated with hyperammonemia.

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Description

Activated by phosphorylation on Thr-211 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius

suggesting either heavy glycosylation or dimerization

and as a transcriptional repressor

ZNHIT1 (Zinc Finger HIT-Type Containing 1) is a Protein Coding gene

NAGS Rabbit Polyclonal Antibody, 20ul sgRNA customized design Activated by phosphorylation on Thr-211The N acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N acetylglutamate (NAG) from glutamate and acetyl coenzyme A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI) the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and thereby CPSI activity. Deficiencies in N acetylglutamate synthase have been associated with hyperammonemia.

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