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KLF8 Polyclonal Antibody, 100ul Deep Well Plates Mutations in this gene are

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KLF8 Polyclonal Antibody, 100ul Deep Well Plates Mutations in this gene areKLF8 encodes Kruppel like factor 8 which is a member of the Sp KLF family of transcription factors. Members of this family contain a C terminal DNA binding domain with three Kruppel like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16.

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Description

Mutations in this gene are associated with X-linked Alport syndrome

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Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported

serine/threonine protein kinase family

ADAM metallopeptidase with thrombospondin type 1 motif 1 encoded by ADAMTS1 contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity

KLF8 Polyclonal Antibody, 100ul Deep Well Plates Mutations in this gene areKLF8 encodes Kruppel like factor 8 which is a member of the Sp KLF family of transcription factors. Members of this family contain a C terminal DNA binding domain with three Kruppel like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16.

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