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EGF Polyclonal Antibody, 100ul[BT-AP15376] Sample Library Tubes Chromosome 7 has been linked

SKU: 72714468340

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EGF Polyclonal Antibody, 100ul[BT-AP15376] Sample Library Tubes Chromosome 7 has been linkedThis gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53 amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects

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Description

Chromosome 7 has been linked to Osteogenesis imperfecta

and may also have a role in immune tolerance at the maternal-fetal interface

Mutations in this gene may contribute to sterol accumulation and atheroschlerosis| and have been observed in patients with sitosterolemia

Expression occurs prior to and is required for expression of pou domain transcription factor 1

Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts

EGF Polyclonal Antibody, 100ul[BT-AP15376] Sample Library Tubes Chromosome 7 has been linkedThis gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53 amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects

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