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UB2R2 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) selectin P ligand plays a

SKU: 73218884570

4.3
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UB2R2 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) selectin P ligand plays aProtein kinase CK2 is a ubiquitous and pleiotropic Ser Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3 CDC34. Studies suggest that CK2 dependent phosphorylation of this ubiquitin conjugating enzyme functions by regulating beta TrCP substrate recognition and induces its interaction with beta TrCP, enhancing beta catenin degradation.

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Description

selectin P ligand plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins

PTM:Phosphorylation at 'Thr-103' and 'Ser-573' is followed by proteasomal degradation

Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype

and may play a general role in the central nervous system

and MAPKAP kinase 2

UB2R2 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) selectin P ligand plays aProtein kinase CK2 is a ubiquitous and pleiotropic Ser Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3 CDC34. Studies suggest that CK2 dependent phosphorylation of this ubiquitin conjugating enzyme functions by regulating beta TrCP substrate recognition and induces its interaction with beta TrCP, enhancing beta catenin degradation.

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