EMR2 Polyclonal Antibody, 20ul[BT-AP02942] Modified Oligos non-receptor tyrosine kinase)is negatively regulated

non-receptor tyrosine kinase)is negatively regulated by its SH3 domain

Defects in TMEM237 are a cause of Joubert syndrome-14

The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis

and isoleucine catabolic pathways

suggesting that they are not conventional components of the extracellular matrix

EMR2 Polyclonal Antibody, 20ul[BT-AP02942] Modified Oligos non-receptor tyrosine kinase)is negatively regulatedADGRE2 encodes a member of the class B seven span transmembrane (TM7) subfamily of G protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N terminal epidermal growth factor like domains coupled to a TM7 domain via a mucin like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell cell adhesion through interaction with chondroitin sulfate