M3K15 Polyclonal Antibody, 20ul Pipette Controller Most MMPs are secreted as

Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases

Downregulation of this gene is associated with breast cancer

May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles

The protein encoded by NDRG2 is a cytoplasmic protein that may play a role in neurite outgrowth

The encoded protein is involved in platelet activation and controls the expression of interleukin-2

M3K15 Polyclonal Antibody, 20ul Pipette Controller Most MMPs are secreted asThe protein encoded by this gene is a member of the mitogen activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses.