ErbB-3 Polyclonal Antibody, 50ul[BT-AP03042] Culture Media and induction of cell cycle

and induction of cell cycle arrest in naive CD8+ cells

This highly conserved protein family is found in both plants and mammals| and this protein is 99% identical to the mouse| rat and sheep orthologs

Contains 1 UBP-type zinc finger

Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome| Donohue syndrome and Rabson-Mendenhall syndrome

Four alternatively spliced transcript variants encoding the same protein have been found for this gene

ErbB-3 Polyclonal Antibody, 50ul[BT-AP03042] Culture Media and induction of cell cycleERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation