Human Serine/Arginine-rich Splicing Factor 1, SFRS1 ELISA Kit , 96T In vitro Transcription CUL-1-mediated ubiquitination results in the

CUL-1-mediated ubiquitination results in the degradation of cell cycle proteins cyclin D

A similar protein in mouse is required for early development of the embryo

Members of this protein family form part of the cytomatrix at the active zone (CAZ) complex and function as regulators of neurotransmitter release

A related protein interacts with calcium/calmodulin-dependent serine protein kinase (CASK)

and function of granulocytes

Human Serine/Arginine-rich Splicing Factor 1, SFRS1 ELISA Kit , 96T In vitro Transcription CUL-1-mediated ubiquitination results in thePlays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5' and 3' splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5' splice site containing pre mRNA. Binds to purine rich RNA sequences, either the octamer, 5' RGAAGAAC 3' (r=A or G) or the decamers, AGGACAGAGC