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Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09130] Cell Culture Flasks The encoded preproprotein is proteolytically

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Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09130] Cell Culture Flasks The encoded preproprotein is proteolyticallyTOP2A encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering

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Description

The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor

They play important roles in intracellular vesicle transport and cell division (summary by Venturelli et al

and DNA ligase I (LIG1) on long-patch base excision repair substrates

which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB

CBR3 contains three exons spanning 11

Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09130] Cell Culture Flasks The encoded preproprotein is proteolyticallyTOP2A encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering

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