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RFOX1 Polyclonal Antibody, 50ul Buffer Solutions Contains 9 ANK repeats

SKU: 75679766099

4.4
USD162.00 USD209.00

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RFOX1 Polyclonal Antibody, 50ul Buffer Solutions Contains 9 ANK repeatsThe Fox 1 family of RNA binding proteins is evolutionarily conserved, and regulates tissue specific alternative splicing in metazoa. Fox 1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C terminus of ataxin 2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin 2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox 1 and ataxin

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Description

Contains 9 ANK repeats

Promotes neuritogenesis in developing hippocampal neurons

as well as X-linked combined immunodeficiency (XCID)

The encoded protein shares a high level of similarity to the rat homolog| and contains 3 C2 domains and a diacylglycerol-binding C1 domain

thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis

RFOX1 Polyclonal Antibody, 50ul Buffer Solutions Contains 9 ANK repeatsThe Fox 1 family of RNA binding proteins is evolutionarily conserved, and regulates tissue specific alternative splicing in metazoa. Fox 1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C terminus of ataxin 2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin 2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox 1 and ataxin

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