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TLK1 Polyclonal Antibody, 50ul[BT-AP09054] Thermal Control PAX1 plays a role in

SKU: 75788465987

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TLK1 Polyclonal Antibody, 50ul[BT-AP09054] Thermal Control PAX1 plays a role inSerine threonine protein kinase tousled like 1 encoded by TLK1 is a serine threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript

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Description

PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm

homeostasis and apoptosis

and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres

which is associated with the fragile X mental retardation syndrome (MIM 300624)

TLK1 Polyclonal Antibody, 50ul[BT-AP09054] Thermal Control PAX1 plays a role inSerine threonine protein kinase tousled like 1 encoded by TLK1 is a serine threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript

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