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DMA Polyclonal Antibody, 20ul Immune Repertoire Sequencing Although this locus appears to

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DMA Polyclonal Antibody, 20ul Immune Repertoire Sequencing Although this locus appears toHLA DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes,

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Description

Although this locus appears to encode a protein similar to trypsinogen| the locus is thought to be a transcribed pseudogene

AKAP11 encodes a member of the AKAP family

PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues

and thrombospondin N-terminal-like domains

Several transcript variants encoding multiple isoforms have been described

DMA Polyclonal Antibody, 20ul Immune Repertoire Sequencing Although this locus appears toHLA DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes,

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