S22AC Rabbit Polyclonal Antibody, 20ul High Speed Micro-Centrifuges Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include antigen binding and immunoglobulin receptor binding

This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates

Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts| cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI)

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

Like other small GTPases

S22AC Rabbit Polyclonal Antibody, 20ul High Speed Micro-Centrifuges Gene Ontology (GO) annotations relatedThe protein encoded by this gene is a member of the organic anion transporter (OAT) family and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate hyperuricemia is associated with increased incidences of gout and mutations in this gene cause renal hypouricemia type 1. Alternative splicing