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NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library an EGF repeat region consisting

SKU: 77470519739

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NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library an EGF repeat region consistingThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments

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Description

an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat| 3 of which have a calcium-binding consensus sequence

Two related serine/threonine kinases

In mice and rats

Studies in mice and human suggest that STEAP4 maybe involved in adipocyte development and metabolism

but not for neutrophils

NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library an EGF repeat region consistingThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments

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