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Keratin 77 Polyclonal Antibody, 20ul CellSafe™ This gene is part of

SKU: 78166676266

4.6
PLN97.20 PLN130.20

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Keratin 77 Polyclonal Antibody, 20ul CellSafe™ This gene is part ofKeratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.

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Description

This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway

A portion of the 3' untranslated region was used to map this gene to chromosome 21q21

Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC

Required for interleukin-2 (IL2) production

The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini

Keratin 77 Polyclonal Antibody, 20ul CellSafe™ This gene is part ofKeratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.

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