PDE1A Polyclonal Antibody, 100ul Isothermal Amplification This gene and the related
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PDE1A Polyclonal Antibody, 100ul Isothermal Amplification This gene and the relatedCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and or cGMP to their respective nucleoside 5 prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+) calmodulin (see CALM1; MIM 114180) dependent PDEs (CaM PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001
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