SH3L2 Polyclonal Antibody, 50ul 3D Culture The preservation of the ORF

The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional| possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis

This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1)

This gene encodes a protein with an N-terminal filamin-binding domain| a central proline-rich domain| and| multiple C-terminal LIM domains

1998 [PubMed: 9616133])

Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia

SH3L2 Polyclonal Antibody, 50ul 3D Culture The preservation of the ORF