CD6 Polyclonal Antibody, 20ul[BT-AP02435] Apoptosis & Autophagy Upon tyrosine phosphorylation

Upon tyrosine phosphorylation

Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage

It functions through either direct interaction with components of the antigen receptor complexes

Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome

a basic domain

CD6 Polyclonal Antibody, 20ul[BT-AP02435] Apoptosis & Autophagy Upon tyrosine phosphorylationPeptidyl prolyl cis trans isomerase B encoded by PPIB is a cyclosporine binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T and B lymphocytes, and may regulate cyclosporine A mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.