Oct-3/4 Polyclonal Antibody, 50ul[BT-AP06332] Multi-Layer Cell Culture System 8-dihydroneopterin triphosphate

8-dihydroneopterin triphosphate

In vitro assays indicate the protein lacks phosphorylation activity

Mutations in this gene are associated with ectodermal dysplasia| and cleft lip/palate syndrome 3 (EEC3)

This protein and RII PKA colocalize at the cell periphery

Eight transcript variants encoding the same protein have been found for this gene

Oct-3/4 Polyclonal Antibody, 50ul[BT-AP06332] Multi-Layer Cell Culture System 8-dihydroneopterin triphosphatePOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG