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MYOC Polyclonal Antibody, 50ul Custom DNA Oligos which is down-regulated in metastatic

SKU: 81122206497

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MYOC Polyclonal Antibody, 50ul Custom DNA Oligos which is down-regulated in metastaticMYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile onset

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Description

which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells

growth retardation

and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons

Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome

Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein

MYOC Polyclonal Antibody, 50ul Custom DNA Oligos which is down-regulated in metastaticMYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile onset

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