PDZK3 Polyclonal Antibody, 100ul Live Cell Imaging The protein encoded by this

The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases

In rat| this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal

This gene maps to the taste receptor gene cluster on chromosome 12p13

Two transcript variants encoding the same protein have been found for APOL2

This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis

PDZK3 Polyclonal Antibody, 100ul Live Cell Imaging The protein encoded by thisThe PDZ domain containing 2 encoded by PDZD2 contains six PDZ domains and shares sequence similarity with pro interleukin 16 (pro IL 16). Like pro IL 16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.