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eIF4A1 Monoclonal Antibody(M8), 20ul CellSafe™ Polymorphisms near this gene are

SKU: 81337695214

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eIF4A1 Monoclonal Antibody(M8), 20ul CellSafe™ Polymorphisms near this gene areATP dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5' UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.,similarity: Belongs to the DEAD box helicase family.,similarity: Belongs to

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Description

Polymorphisms near this gene are associated with pre-eclampsia in female human patients

Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome

chicken and zebrafish

or intellectual problems

including neurotransmission

eIF4A1 Monoclonal Antibody(M8), 20ul CellSafe™ Polymorphisms near this gene areATP dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5' UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.,similarity: Belongs to the DEAD box helicase family.,similarity: Belongs to

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