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ORAOV1 Polyclonal Antibody, 50ul ADME The protein encoded by this

SKU: 82128001840

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ORAOV1 Polyclonal Antibody, 50ul ADME The protein encoded by thisSLC22A18 is one of several tumor suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor suppressor gene region. Alterations in this region have been associated with the Beckwith Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in SLC22A18 have been

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Description

The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins

This factor is converted to an active form by factor XIa| which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds

as well as in the control of gene transcription

This locus represents a member of the cancer/testis gene family 47

ORAOV1 Polyclonal Antibody, 50ul ADME The protein encoded by thisSLC22A18 is one of several tumor suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor suppressor gene region. Alterations in this region have been associated with the Beckwith Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in SLC22A18 have been

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