JAK3 Polyclonal Antibody, 100ul Glassware Activins are dimeric growth and

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins

Mutations in PMS2 have been associated with hereditary nonpolyposis colorectal cancer (HNPCC

resulting in several non-synonymous codon differences among individuals of different genetic backgrounds

TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB

Interacts with SNRNP70 in apoptotic cells (By similarity)

JAK3 Polyclonal Antibody, 100ul Glassware Activins are dimeric growth andThe protein encoded by JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).