LC3 A/B Rabbit Polyclonal Antibody, 20ul[BT-AP03381] Variant Libraries TOP1 (topoisomerase (DNA) I) encodes

TOP1 (topoisomerase (DNA) I) encodes a DNA topoisomerase

trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR)

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calcium-mobilizing protein (VACM-1)

Increased expression of this gene has been correlated with malignant progression of prostate tumors

LC3 A/B Rabbit Polyclonal Antibody, 20ul[BT-AP03381] Variant Libraries TOP1 (topoisomerase (DNA) I) encodesProbably involved in formation of autophagosomal vacuoles (autophagosomes). PTM: The precursor molecule is cleaved by APG4B ATG4B to form the cytosolic form LC3 I. This is activated by APG7L ATG7 transferred to ATG3 and conjugated to phospholipid to form the membrane bound form LC3 II. Belongs to the MAP1 LC3 family. subcellular location: LC3 II binds to the autophagic membranes. subunit: 3 different light chains LC1 LC2 and LC3 can associate with