Aven Polyclonal Antibody, 50ul Bio-Reaction Tube Two pseudogenes of this gene

Two pseudogenes of this gene have been identified on chromosomes 10 and 4

through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli

and peripheral neuropathy

Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding

They may participate in fatty acyl and cholesterol ester metabolism

Aven Polyclonal Antibody, 50ul Bio-Reaction Tube Two pseudogenes of this geneAVEN, a cell death regulator, is an important signal inducer in acute leuke mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf 1 mediated apoptosis by interfering with Apaf 1's ability to self associate. Bcl 2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be