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BCL2L12 Polyclonal Antibody, 100ul Nucleic Acid Extraction The encoded protein binds to

SKU: 82454382150

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BCL2L12 Polyclonal Antibody, 100ul Nucleic Acid Extraction The encoded protein binds toBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl 2 homology domain 2 (BH2). The encoded protein is an anti apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome

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Description

The encoded protein binds to the enhancer region of the insulin gene

and the two forms likely arise from the use of alternative translation initiation sites

including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion

VGF is specifically expressed in a subpopulation of neuroendocrine cells

Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway

BCL2L12 Polyclonal Antibody, 100ul Nucleic Acid Extraction The encoded protein binds toBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl 2 homology domain 2 (BH2). The encoded protein is an anti apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome

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