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PRMT4 Monoclonal Antibody, 50ul[BT-MCA1065] Filtration Defects in this gene cause

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PRMT4 Monoclonal Antibody, 50ul[BT-MCA1065] Filtration Defects in this gene causeThis gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi protein complexes and may play a role in cell type specific functions and cell

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Description

Defects in this gene cause aortic aneurysm familial thoracic type 6

RERGL binds GDP/GTP and may possess intrinsic GTPase activity

It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits

and a cysteine-rich C-terminal domain

WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in actin polymerization and cytoskeletal organization

PRMT4 Monoclonal Antibody, 50ul[BT-MCA1065] Filtration Defects in this gene causeThis gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi protein complexes and may play a role in cell type specific functions and cell

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