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BCAS3 Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene are

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BCAS3 Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene areRudhira BCAS3 (Breast Cancer Amplified Sequence 3) is a conserved protein expressed in the embryonic vasculature and malignant tumors. Rudhira is a predicted WD40 domain protein. During mouse development Rudhira is expressed in erythropoietic and angiogenic precursors but not in their differentiated progeny. This transient expression of Rudhira is also seen in normal adult angiogenesis. BCAS3, the human ortholog of Rudhira is 98% identical and the

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Description

Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia

encoded by two separate genes

The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the biogenesis of the 60S ribosomal subunit

obesity and blood clotting disorders

and mutations in this gene are a cause of hereditary leukonychia

BCAS3 Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene areRudhira BCAS3 (Breast Cancer Amplified Sequence 3) is a conserved protein expressed in the embryonic vasculature and malignant tumors. Rudhira is a predicted WD40 domain protein. During mouse development Rudhira is expressed in erythropoietic and angiogenic precursors but not in their differentiated progeny. This transient expression of Rudhira is also seen in normal adult angiogenesis. BCAS3, the human ortholog of Rudhira is 98% identical and the

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