Human Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Human Genome Knockout Libraries including SMAD1 and POU4F1/Brn3a and
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Human Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Human Genome Knockout Libraries including SMAD1 and POU4F1/Brn3a andABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane (PubMed: 27144356). Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11138003, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed:
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