CE104 Rabbit Polyclonal Antibody, 100ul Metabolic enzymes The encoded protein couples with

The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway

In humans| polymorphisms in this gene are associated with variation in human height and osteoarthritis

and the testis

This protein may also function independently of dynein as a transcriptional modulator

In addition| using a separate promoter in an intron in the 3' region| it encodes telokin| a small protein identical in sequence to the C-terminus of myosin light chain kinase| that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments

CE104 Rabbit Polyclonal Antibody, 100ul Metabolic enzymes The encoded protein couples withThis gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino terminal hydrophobic domains, two glycosylation sites, four cysteine rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium.