p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11731] Monoclonal Antibody Preparation and has glycosaminoglycan attachment sites

and has glycosaminoglycan attachment sites in the acidic C-terminal region

ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors

The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide

This enzyme is localized to the mitochondria and may play a role in programmed cell death

Four different regulatory subunits and three catalytic subunits have been identified in humans

p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11731] Monoclonal Antibody Preparation and has glycosaminoglycan attachment sitesThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative