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TBCD7 Rabbit Polyclonal Antibody, 50ul Purification BECN1 (beclin 1) encodes a

SKU: 84427739413

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TBCD7 Rabbit Polyclonal Antibody, 50ul Purification BECN1 (beclin 1) encodes aThis gene encodes a member of the TBC domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1 TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus

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Description

BECN1 (beclin 1) encodes a protein that regulates autophagy

strengthening and stabilizing the pericentriolar region prior to spindle formation

including steroid

Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis

This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism| synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney

TBCD7 Rabbit Polyclonal Antibody, 50ul Purification BECN1 (beclin 1) encodes aThis gene encodes a member of the TBC domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1 TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus

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