BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 50ul Serum The gene is located in

The gene is located in a region deleted in pediatric rhabdoid tumors of the brain

10 µm PVDF membrane

or receptor scavenging

that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA

three pseudogenes are located on chromosomes 9

BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 50ul Serum The gene is located inIntact BH3 motif is required by BIK BID BAK BAD and BAX for their pro apoptotic activity and for their interaction with anti apoptotic members of the Bcl 2 family. The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1 isoform 2 and isoform 4 induce ICE like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl 2. PTM: Phosphorylated upon DNA damage probably by