MCR Polyclonal Antibody, 100ul CellSafe™ Involved in the RCC1/Ran-GTPase pathway

Involved in the RCC1/Ran-GTPase pathway

but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1

but lacks cytoplasmic domain

Contactins mediate cell surface interactions during nervous system development

tissue specificity:Expressed predominantly in brain

MCR Polyclonal Antibody, 100ul CellSafe™ Involved in the RCC1/Ran-GTPase pathwayThis gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are