IF2B1 Polyclonal Antibody, 20ul Cell Separation and Collection TOP2A encoding this enzyme functions

TOP2A encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

A pseudogene of this gene is present on chromosome 2

and formats to cater to diverse research requirements

The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis

The encoded protein may function as a transcription factor

IF2B1 Polyclonal Antibody, 20ul Cell Separation and Collection TOP2A encoding this enzyme functionsThis gene encodes a member of the insulin like growth factor 2 mRNA binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes including insulin like growth factor 2 beta actin and beta transducin repeat containing protein and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.