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TFIIA- Alpha Polyclonal Antibody, 100ul Long RNA Synthesis Defects in this protein or

SKU: 85788485094

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SEK123.75 SEK160.75

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TFIIA- Alpha Polyclonal Antibody, 100ul Long RNA Synthesis Defects in this protein orAccurate transcription initiation on TATA containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35 , 19 , and 12 kD subunits.

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Description

Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE)

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins

is also included in the cullin family as it shares substantial sequence homology with CUL-1

Introducing the PS1

CACTIN (Cactin

TFIIA- Alpha Polyclonal Antibody, 100ul Long RNA Synthesis Defects in this protein orAccurate transcription initiation on TATA containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35 , 19 , and 12 kD subunits.

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