MYO10 Polyclonal Antibody, 100ul Enzyme Activity Assays identified as a major autoantigen

identified as a major autoantigen in insulin-dependent diabetes

Two related pseudogenes have been identified on chromosome 16

consisting of seven genes belonging to the expanding B7/butyrophilin-like group

where it regulates integrin-mediated signal transduction

The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712)

MYO10 Polyclonal Antibody, 100ul Enzyme Activity Assays identified as a major autoantigenThis gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non muscle myosin 10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin based molecular motor and plays a role in integration of F actin and microtubule cytoskeletons