p14 Polyclonal Antibody, 20ul Metabolic enzymes Both Ikaros and Aiolos can

Both Ikaros and Aiolos can participate in chromatin remodeling

but our experiment always detected a 60-70kDa protein by western blot

Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines

fungi and viruses

Alternative splicing results in multiple variants

p14 Polyclonal Antibody, 20ul Metabolic enzymes Both Ikaros and Aiolos canCDKN2A generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that