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CUL4B is a member of the cullin family

Among its related pathways are Metabolism of proteins and O-linked glycosylation

These transcription factors share a leucine zipper region that is involved in protein-protein interactions

and is thought to regulate cell motility

IGF-IR Polyclonal Antibody, 20ul[BT-AP04398] Custom Peptide Synthesis Take on any challenge inIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms