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Within mitochondria the enzyme glutaminase (GLS) acts on glutamine to produce -ketoglutarate (-KG), and -KG subsequently enters the TCA cycle to support energy production and anaplerosis

Chemicals for preparation of mobile phases (all with purity for LC-MS) and for sample preparation, including acetonitrile (ACN), ultrapure deionized water, FA, difluoroacetic acid (DFA), TFA, SSA, MPA, bovine serum albumin (BSA), and minimum essential medium, were also obtained from Merck (Darmstadt, Germany)

Intramedullary melanotic schwannoma: case report and review of the literature