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GLI-1 Polyclonal Antibody, 50ul Cryopreservation C/EBP proteins contain the bZIP

SKU: 86666871058

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GLI-1 Polyclonal Antibody, 50ul Cryopreservation C/EBP proteins contain the bZIPThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

C/EBP proteins contain the bZIP region

which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates

Ectopic expression of CDKN2C was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function

and may play a general role in the central nervous system

The protein encoded by JAKMIP2 (janus kinase and microtubule interacting protein 2) is reported to be a component of the Golgi matrix

GLI-1 Polyclonal Antibody, 50ul Cryopreservation C/EBP proteins contain the bZIPThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

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