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Paxillin(Phospho Ser178) Polyclonal Antibody, 100ul Stepper subcellular location:Present on the membrane

SKU: 86908874066

4.7
PLN141.00 PLN187.00

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Paxillin(Phospho Ser178) Polyclonal Antibody, 100ul Stepper subcellular location:Present on the membraneThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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Description

subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane

5 mL micro centrifuge tubes

This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1

disease:Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6)

Also found in epidermal basal layer keratinocytes in skin disorders

Paxillin(Phospho Ser178) Polyclonal Antibody, 100ul Stepper subcellular location:Present on the membraneThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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