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Raf-1 Polyclonal Antibody, 50ul[BT-AP13532] Liquid Handling &Storage Additional splice variants have been

SKU: 86940369511

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Raf-1 Polyclonal Antibody, 50ul[BT-AP13532] Liquid Handling &Storage Additional splice variants have beenThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

Additional splice variants have been described but sequences for the complete transcripts have not been determined

which induces NF-kappaB activation and cell death initiated by LTbeta ligation

The intermediate and light chains

KCNIP1 encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs)

The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling

Raf-1 Polyclonal Antibody, 50ul[BT-AP13532] Liquid Handling &Storage Additional splice variants have beenThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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