Desmoplakin(Phospho-Ser165/166) Rabbit Polyclonal Antibody, 50ul Antibody Humanization a highly conserved protein complex

a highly conserved protein complex that functions as an important regulator in multiple signaling pathways

which may indicate an additional role in integrin signaling pathways

Alternate splicing of this gene results in two transcript variants encoding different isoforms

and it is therefore considered to be a therapeutic target

CHP2 was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520

Desmoplakin(Phospho-Ser165/166) Rabbit Polyclonal Antibody, 50ul Antibody Humanization a highly conserved protein complexThis gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas including skin fragility woolly hair syndrome. Alternative splicing results in multiple transcript variants.