DDR1 Polyclonal Antibody, 50ul[BT-AP02536] Roller Bottles Defects in CLCF1 cause cold-induced

Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2)

acquired idiopathic sideroblastic anemia

The encoded protein shares 100% sequence identity with the mouse and rat counterparts

The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1| which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis

Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome

DDR1 Polyclonal Antibody, 50ul[BT-AP02536] Roller Bottles Defects in CLCF1 cause cold-inducedReceptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Discoidin domain receptor tyrosine kinase 1 encoded by DDR1 belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen.