ALK Polyclonal Antibody, 50ul[BT-AP00371] Culture Plate Inserts The protein encoded by this

The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B

The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus

studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras

More importantly| the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product| restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo

thymus and peripheral blood

ALK Polyclonal Antibody, 50ul[BT-AP00371] Culture Plate Inserts The protein encoded by thisALK encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. ALK tyrosine kinase receptor comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or